VHIO’s BENCHSTORMING SEMINARS

Launched in February 2016 by co-Chairs and Founders Verónica Rodilla and Jordi Martínez Quintanilla, Post-Doctoral Fellows of VHIO´s Growth Factors and Stem Cells & Cancer Groups respectively, our series of Benchstoming Seminars represent an excellent educational opportunity for junior faculty at VHIO to both present and exchange on and around their respective research interests across VHIO´s various research programs.

Not only do our young researchers learn more about their other colleagues and research lines currently underway, they can also express their ideas surrounding a given topic presented at each seminar; the specially crafted informal format favors free thought, flow, and interaction between the speakers and participants.

New Benchstorming co-Chairs, Elena Senís and Toni Jauset

As the Benchstormings turned two years old, Verónica and Jordi handed over to new Benchstorming co-Chairs in March 2018, Elena Senís, Post-Doctoral Fellow of VHIO’s Cellular Plasticity & Cancer Group, and Toni Jauset, formerly a graduate student of VHIO’s Mouse Models of Cancer Therapies Group and now researcher at VHIO-born spin-off Peptomyc S.L.

 

 

 

 

 


  • Date: Thursday 11th January
  • Speaker: Gemma Serra, PhD Student, Chromatin Dynamics in Cancer Group, PI: Sandra Peiró
  • Talk title: Characterization of the molecular mechanisms underlying LOXL2-dependent chromatin reorganization

  • Date: Thursday 8th February
  • Speaker: Mireia Pujals, PhD Student, Tumor Biomarkers Group, PI: Josep Villanueva
  • Talk title: The impact of tumor microenvironmental stress on the cancer secretome

  • Date: Thursday 8th March
  • Speaker: Juan Nieto, Post-Doctoral Scientist, VHIO’s Experimental Hematology Group, PI: Francesc Bosch
  • Talk title: Modulation of the immune response using cyclophosphamide after allogeneic stem cell transplantation in Hodgkin’s lymphoma patients previously treated with nivolumab

  • Date: Thursday 05th April
  • Speaker: Cristina Cruz, Medical Oncologist and Staff Scientist of VHIO’s Experimental Therapeutics and High Risk & Cancer Prevention Groups (PIs: Violeta Serra and Judith Balmaña, respectively).
  • Talk title: Understanding the biology of hereditary BRCA breast cancers

  • Date: Thursday 26th April
  • Speakers: Benchstorming co-Chairs, Elena Senís and Toni Jauset
  • Talk title: Refresher mini-masterclass with tips and tricks for preparing Benchstorming presentations

  • Date: Thursday 10th May
  • Speaker: Toni Jauset, VHIO-born spin-off Peptomyc S.L. (CEO: Laura Soucek, CSO: Marie-Eve Beaulieu)
  • Talk title: The role of Fzd9 in Myc-induced tumorigenesis

  • Date: Wednesday 23rd  May
  • Speaker: Albert Gris-Oliver, Post-Doctoral Fellow, Experimental Therapeutics Group (PI: Violeta Serra)
  • Talk title: PI3K/AKT pathway activation determines the sensitivity to AZD5363 (AKT inhibitor)

  • Date: Thursday 7th June
  • Speaker: Verónica Rodilla, PhD (Joaquín Arribas Lab)
  • Talk title: In vivo models to study OIS and TIS in breast cancer

  • Date: Thursday 5th July
  • Speaker: Regina Mayor, Post-Doctoral Fellow, Gene Expression & Cancer Group, PI: Joan Seoane
  • Talk title: Cerebrospinal fluid ctDNA: a potent tool for the molecular diagnostics of gliomas

  • Date: Thursday 19th  July
  • Speaker: Isabel Puig, Post-Doctoral Fellow, Stem Cells & Cancer Group, PI: Héctor G. Palmer
  • Talk title: TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence

  • Date: Thursday 27th September
  • Speaker: Jordi Martínez Quintanilla, Post-Doctoral Fellow, Stem Cells & Cancer Group (PI:  Héctor G. Palmer) & Faiz Bilal, Graduate Student, Growth Factors Group (PI: Joaquín Arribas)
  • Benchstorming Seminar type: Techstorming
  • Talk title: How to make organoids from healthy & tumor tissue

  • Date: Thursday 4th October
  • Speaker: Alejandro Athie, Post-Doctoral Fellow, Prostate Cancer Translational Research Group, PI: Joaquin Mateo
  • Talk title: Somatic copy-number alterations from an IncRNA perspective

  • Date: Thursday 18th October
  • Speaker: Samuel Ribeiro, Post-Doctoral Fellow, Applied Genetics of Metastatic Cancer Group, PI: Leticia de Mattos-Arruda
  • Talk title: Tumor microenvironment: a key approach to understanding cancer treatment response modulation

  • Date: Wednesday 31 October
  • Speaker: Marta Ligero & Alonso García, Radiomics Group, PI: Raquel Perez-Lopez
  • Talk title: The path from medical imaging to precision medicine

  • Date: Thursday 15 November
  • Speaker: Maria Lozano, Graduate Student, Tumor Immunology & Immunotherapy Group, PI: Alena Gros
  • Talk title: Identification of personalized tumor rejection antigens through immunopeptidomics


Date: Thursday 12th January

Speaker: Alba LLop, Post-Doctoral Fellow, VHIO´s Experimental Therapeutics Group, PI: Violeta Serra

Talk title: Deep sea as a source of novel anticancer drugs: lurbinectedin in BRCA-mutated breast cancer


Date: Thursday 26th January

Speaker: Olga Méndez, Post-Doctoral Fellow, VHIO´s Tumor Biomarkers Group, PI: Josep Villanueva

Talk title: Non-classical secretion in breast cancer invasion


Date: Thursday 9th February

Speaker: Mónica Sánchez, PhD Student, VHIO´s Experimental Therapeutics Group, PI: Violeta Serra

Talk title: Targeting PI3K in breast cancer: mechanisms of primary and acquired resistance


Date: Thursday 2nd March

Speaker: Alfonso García, Masters Student, VHIO´s Growth Factors Group, PI: Joaquín Arribas

Talk title: Switch Pocket Inhibitor to overcome Kit heterogeneity mutations in Imatinib resistant GIST


Date: Thursday 16th March

Speaker: Marta Palafox, Post-Doctoral Fellow, VHIO´s Experimental Therapeutics Group, PI: Violeta Serra

Talk title: Identification and validation of biomarkers of response to CDK4/6 inhibitors in ER+ and Her2+ Breast Cancer


Date: Thursday 30th March

Speaker: Silvia Casacuberta, Post-Doctoral Fellow, VHIO´s Mouse Models of Cancer Therapies Group, PI: Laura Soucek

Talk title: Myc inhibition by Omomyc and the immune system


Date: Thursday 27th April

Speaker: Gemma Montalban, PhD Student, VHIO´s Oncogenetics Group, PI: Orland Díez

Talk title: Investigating pathogenicity of BRCA1/2 splicing variants in familial breast and ovarian cancers


Date: Thursday 11th May

Speaker: Gaetano Verde, Post-Doctoral Fellow, VHIO´s Chromatin Dynamics in Cancer Group, PI: Sandra Peiró

Talk title: Progesterone receptor maintains estrogen receptor
gene expression in breast cancer cells by regulating
DNA methylation in the absence of hormones


Date: Thursday 25th May

Speaker: Emanuela Greco, PhD Student, VHIO´s Cellular Plasticity & Cancer Group, PI: María Abad

Talk title: Finding IncRNAs that encode micropeptides: MIDORI, an anitsense story that makes sense


Date: Thursday 8th June

Speaker: Isabel Jimenez, PhD Student, VHIO´s Experimental Hematology Group, PI: Francesc Bosch

Talk title: Exploring the role of immunosuppression in clinical progression of Chronic Lymphocytic Leukemia


Date: Thursday 22nd June

Speaker: Mercedes Nadal, Post-Doctoral Fellow, VHIO´s Growth Factors Group, PI: Joaquín Arribas

Talk title: Characterization of resistances to antibody-drug conjugates (ADCs) targeting HER2


Date: Thursday 6th July

Speaker: Olga Boix, PhD Student, VHIO´s Cellular Plasticity & Cancer Group, PI: María Abad

Talk title: DNMTR, a novel micropeptide that kisses cancer cells to death


Date: Thursday 21st September

Speaker: Carlos Alberto Fajardo, Post-Doctoral Fellow, Tumor Immunology and Immunotherapy Group, PI: Alena Gros

Talk title: Novel viro- and immunotherapies of cancer: preclinical development and evaluation of immune responses in cancer patients


Date: Thursday 5th October

Speaker: Juan Manuel Duran, Post-Doctoral Fellow, VHIO´s Tumor Biomarkers Group, PI: Josep Villanueva

Talk title: LAMP2 and unconventional secretion in breast cancer


Date: Thursday 26th October

Speaker: Sandra Bonache, Post-Doctoral Fellow, Oncogenetics Group, PI: Orland Díez

Talk title: Finding new genetic variants in hereditary breast and ovarian cancer


Date: Thursday 2nd November

Speaker: Laura Pascual, PhD Student, Chromatin Dynamics in Cancer Group, PI: Sandra Peiró

Talk title: Role of euchromatin LaminB1 in EMT


Date: Thursday 23rd November

Speaker: Iñaki Merino, Graduate Student, Cellular Plasticity and Cancer Group, PI: María Abad

Talk title: Masala micropeptide: A novel p21 regulator to spice up tumour suppression


In 2016, a total of 16 researchers presented, discussed and ´benchstormed´ their research areas as follows:


Date: Thursday 4th February

Speaker: Verónica Rodilla, Post-Doctoral Fellow, VHIO´s Growth Factors Group, PI: Joaquín Arribas

Talk title: Studying the consequences of killing senescent cells at different 6me points of tumor development in vivo


Date: Thursday 18th February

Speaker: Jordi Martínez Quintanilla, Post-Doctoral Fellow, VHIO´s Stem Cells & Cancer Group, PI: Héctor G. Palmer

Talk title: Therapeutic inhibition of the oncogenic Wnt/β-catenin pathway in mismatch repair deficient hypermutant tumors


Date: Thursday 3rd March

Speaker: Marie-Eve Beaulieu, Co-Founder & Chief Scientific Officer (CSO) of Peptomyc S.L

Talk title: Pushing Myc inhibition to the clinic


Date: Thursday 17th March

Speaker:  Albert Gris, Graduate Student, Experimental Therapeutics Group, PI: Violeta Serra

Talk title: PI3K blockade reverses primary resistance and adaptation to Eribulin treatment in PIK3CA mutant breast cancer tumors


Date: Thursday 14th April

Speaker: Mariano F. Zacarías, Postdoctoral Fellow, VHIO´s Mouse Models of Cancer Therapies Group, PI: Laura Soucek

Talk title: Targeting Myc in Melanoma


Date: Thursday 12th May

Speaker: Estefania Cuesta, Predoctoral Fellow, VHIO´s Stem Cells & Cancer Group, PI: Héctor G. Palmer

Talk title:  Molecular mechanisms responsible for cancer cell dormancy


Date: Thursday 2nd June

Speaker: César Serrano, Medical Oncologist, VHIO´s Growth Factors Group, PI: Joaquín Arribas

Talk title: Targeting heterogeneity in imatinib-resistant GIST patients


Date: Thursday 16th June

Speaker: Mercè Juliachs, Postdoctoral Fellow, VHIO´s Tumor Biomarkers Group, PI: Josep Villanueva

Talk title: Extracellular SOD2 is induced by the tumor microenvironment and mediates tumor migration in invasive breast cancer cell lines


Date: Thursday 30th June

Speaker: Faiz Bilal, Graduate Student, VHIO´s Growth Factors Group, PI: Joaquín Arribas

Talk title: Exploring the mechanisms of resistance to MEK inhibition in pancreatic cancer


Date: Thursday 22nd September

Speaker: Toni Jauset, Graduate Student, VHIO´s Mouse Models of Cancer Therapies Group, PI: Laura Soucek

Talk title: Investigating the therapeutic potential and mechanism of action of Omomyc-based Myc inhibition in lung cancer


Date: Thursday 6th October

Speaker: Oriol Arqués, Post-Doctoral Fellow

Talk title: Therapeutic inhibition of WNT and NOTCH pathways in colorectal cancer


Date: Thursday 20th October

Speaker: Irene Rius, Graduate Student, VHIO´s Growth Factors Group, PI: Joaquín Arribas

Talk title: Functional characterization of HER3 mutations in human cancers


Date: Thursday 3rd November

Speaker: Daniel Massó Vallés, Graduate Student, VHIO´s Mouse Models of Cancer Therapies Group, PI: Laura Soucek

Talk title: Inhibiting Myc and Myc dependent inflammatory response as cancer therapies


Date: Thursday 17th November

Speaker: Elena Senís, Postdoctoral Fellow, VHIO´s Cellular Plasticity & Cancer Group, PI: Maria Abad

Talk title: A toolbox to induce dedifferentiation and its application in cancer


Date: Thursday 1st December

Speaker: Beatriz Morancho, Post-Doctoral Fellow, VHIO´s Growth Factors Group, PI: Joaquín Arribas

Talk title: Immunotherapy to treat cancer


Date: Thursday 15th December

Speaker: Marta Castroviejo, Graduate Student, VHIO´s Experimental Therapeutics Group, PI: Violeta Serra

Talk title: RAD51 as predictive biomarker of response to PARP inhibition