Home > Research Team > Héctor G. Palmer
Academic Qualifications
- Degree in Biological Sciences from the Autonomous University of Barcelona, 1997
- Doctorate in Biochemistry and Molecular Biology from the Autonomous University of Madrid, 2001
- Postdoctoral studies at the Biomedical Research Institute (CSIC-UAM, Madrid), 2001-2003, and at the London Research Institute-Cancer Research UK, 2004-2008
Areas of Research
- New molecular mechanisms of action of the Wnt/beta-catenin pathway in colon cancer
- Role of cancer stem cells in initiation, progression, metastasis and resistance to anti-tumor agents in colon cancer
- Key signalling pathways in induction and maintenance of quiescence and chemoresistance of normal and cancer stem cells
Prizes and Scholarships
- Marie Curie Intra-European (2004)
- Cancer Research UK (2005)
Most relevant scientific publications
- Barbáchano A, Ordóñez-Morán P, García JM, Sánchez A, Pereira F, Larriba MJ, Martínez N, Hernández J, Landolfi S, Bonilla F, Pálmer HG, Rojas JM, Muñoz A. SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity. Oncogene 2010 Aug; 29(34): 4800-13
- Pálmer HG, Anjos-Afonso F, Carmeliet G, Takeda H, Watt FM. The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. PLoS ONE 2008; 3(1): e1483
- Pálmer HG, Larriba MJ, García JM, Ordóñez-Morán P, Peña C, Peiró S, Puig I, Rodríguez R, de la Fuente R, Bernad A, Pollán M, Bonilla F, Gamallo C, de Herreros AG, Muñoz A. The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer. Nat. Med. 2004 Sep; 10(9): 917-9
- Pálmer HG, González-Sancho JM, Espada J, Berciano MT, Puig I, Baulida J, Quintanilla M, Cano A, de Herreros AG, Lafarga M, Muñoz A. Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. J. Cell Biol. 2001 Jul; 154(2): 369-87
