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Radiation Oncology Group

Strategic Goals

  1. Technology developments: Highly conformal radiotherapy
  2. Translational research: EGFR inhibitors plus radiotherapy

Current objectives

  • Continue with the IMRT program in pediatric, gynecology and gastrointestinal tumors.
  • Develop the extracranial stereotactic radiotherapy program in lung cancer and liver metastases.
  • Improve quality control programs and develop new techniques.
  • Study new therapeutic combinations with radiotherapy and EGFR inhibitors in head and neck cancer and gastrointestinal tumors.

Team

Jordi Giralt

Principal Investigator

Radiation Oncologists

  • Sergi Benavente MD
  • Ramón Bodi MD
  • Xavier Maldonado MD
  • Meritxell Molla, MD PhD
  • Begoña Navalpotro MD
  • Mónica Ramos MD
  • Victoria Reyes MD
  • Ramona Verges MD

Publications

  • Rivera F, Galán M, Tabernero J, Cervantes A, Vega-Villegas ME, Gallego J, Laquente B, Rodríguez E, Carrato A, Escudero P, Massuti B, Alonso-Orduña V, Cardenal A, Sáenz A, Giralt J, Yuste AL, Antón A, Aranda E. Phase II trial of preoperative irinotecan-cisplatin followed by concurrent irinotecan-cisplatin and radiotherapy for resectable locally advanced gastric and esophagogastric junction adenocarcinoma. Int. J. Radiat. Oncol. Biol. Phys. 2009 Dec; 75(5): 1430-6
  • Varela E, Antolín M, Guarner F, Verges R, Giralt J, Malagelada JR. Faecal DNA and calprotectin as biomarkers of acute intestinal toxicity in patients undergoing pelvic radiotherapy. Aliment. Pharmacol. Ther. 2009 Jul; 30(2): 175-85
  • Benavente S, Verges R, Hermosilla E, Fumanal V, Casanova N, Garcia A, Ramón y Cajal S, Giralt J. Overexpression of phosphorylated 4E-BP1 predicts for tumor recurrence and reduced survival in cervical carcinoma treated with postoperative radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 2009 Dec; 75(5): 1316-22
  • Guarner L, Navalpotro B, Molero X, Giralt J, Malagelada JR. Management of painful chronic pancreatitis with single-dose radiotherapy. Am. J. Gastroenterol. 2009 Feb; 104(2): 349-55
  • Benavente S, Huang S, Armstrong EA, Chi A, Hsu KT, Wheeler DL, Harari PM. Establishment and characterization of a model of acquired resistance to epidermal growth factor receptor targeting agents in human cancer cells. Clin. Cancer Res. 2009 Mar; 15(5): 1585-92